ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENINGON SOME SUDANESE MEDICINAL PLANTS ETHANOLIC EXTRACTS AGAINST SELECTED HUMAN PATHOGENS
NAGAT. A. ELROFAEI
Department of Biotechnology, Faculty of Science and Technology, Omdurman Islamic University, 382, Omdurman, Sudan
AHMED A. ELSHIKH *
Department of Microbiology, Faculty of Pure and Applied Sciences, International University of Africa, 2469, Khartoum, Sudan
KAUTHER H. ELSHARIF
Department of Biotechnology, Faculty of Science and Technology, Omdurman Islamic University, 382, Omdurman, Sudan
IBRAHIM F. AHMED
Department of Microbiology, Faculty of Medicine Laboratory Sciences, International University of Africa, 2469, Khartoum, Sudan
*Author to whom correspondence should be addressed.
Abstract
The present study was designed to investigate antimicrobial activity of ten Sudanese medicine plant. The ethanolic plant extracts were seasoned against medically important bacteria viz. Streptococcus sp., Staphylococcus sp., Escherichia coli., Pseudomonas sp., and fungi. Candida sp., using cup-plate agar diffusion method. The qualitative phytochemical analyses of ten plant ethanolic extracts were determined.Ethanolic extract showed highest activities against bacteria and fungi. The results of phytochemical screening showed that all extracts of studied plant contain alkaloids, flavonoids, tannins, saponins, anthraquinones. This study give rise to antimicrobial properties of studied plant, and showed interesting correlation with the phytochemical constituents and biological activities.
Keywords: Medicinal plant, antimicrobial activity, phytochemical studies, Sudan