POTENTIAL MICROBIAL APPLICATIONS OF METAL COMPLEXES CONTAINING AMINO ACID DERIVED SCHIFF BASE LIGANDS: AN OVERVIEW
MD. SADDAM HOSSAIN
Department of Chemistry, Begum Rokeya University, Rangpur, Bangladesh.
MD. NUR AMIN BITU
Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
MD. MAHASIN ALI
Department of Chemistry, Hajee Mohammad Danesh Science and Technology University, Bangladesh.
MD. FARUK HOSSEN
Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
MD. ALI ASRAF
Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
MD. ABDUL MANNAN
Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
MD. KUDRAT-E-ZAHAN
Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Antibiotic resistance has dropped dramatically day by day at an alarming rate. In this view there is a strong need to prepare new compounds that not only have potential activity, but having new appliances of action. Inorganic compounds particularly metal complexes have played a significant role in the improvement of potential metal based drugs. The aim of this review is to focus on research undertaken over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor activity of metal complexes containing Schiff base ligands derived from amino acids.
Keywords: Amino acids, Schiff base, anti-cancer, DNA-interaction and antimicrobial activity