Tridax procumbens LEAF EXTRACT BASED BACTERIAL CELLULOSE FOR WOUND HEALING
B. E. RANGASWAMY
Bapuji Institute of Engineering and Technology, Davangere - 577005, Karnataka, India
K. P. VANITHA *
Research Scholar, Bapuji Institute of Engineering and Technology, Davangere - 577005, Karnataka, India
*Author to whom correspondence should be addressed.
Bacterial cellulose is a biopolymer produced from of Gluconoacetobacter sp. RV28 has versatile application in the biomedical field. The bacterial cellulose biocompatibility, water holding capability, never dried gel, microfiber structure make it suits for scaffolds for tissue engineering, carriers for drug delivery, neuron protection, vascular grafts and wound healing. Moreover the bacterial cellulose alone itself not having any antimicrobial activity the implementation of antimicrobial agent is required for its effect. The Tridax procumbens leaf extract was known for its wound healing activity from ancient days, this idea were utilized in the present study to achieve wound healing activity. In this connection the present study represents bacterial gelimmersion in ethanol and methanol leaf extract of Tridax procumbens for 48 h and examined for its antimicrobial effect. The Tridax procumbens based bacterial cellulose showed strong antimicrobial activity against Staphylococcus aureus (Gram-positive). Candida albicans (Yeast) and Pseudomonas aeruginosa; E. coli (Gram-negative). Hence this Tridax procumbens based biopolymer is excellent product for wound healing activity.
Keywords: Bacterial cellulose, Tridax procumbens, Gluconoacetobacter sp. RV28