Integrating Real-Time Data and Machine Learning in Predicting Infectious Disease Outbreaks: Enhancing Response Strategies in Sub-Saharan Africa

Olabisi Promise Lawal *

Department of Medical Laboratory Science, University of Benin, Benin City, Nigeria.

Ejikeme Peter Igwe

Department of Applied Biochemistry, Faculty of Natural Sciences, Enugu State University of Science and Technology, Nigeria.

Adedapo Olosunde

Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH 43606, USA.

Ezeamii Patra Chisom

Department of Biostatistics, Epidemiology and Environmental Health Sciences, Jiann-Ping Hsu College of Public Health, Georgia Southern University, USA.

Debra Ukamaka Okeh

Corona Management Systems, Abuja, Nigeria.

Adepeju Kafayat OLOWOOKERE

University of North Carolina at Greensboro, Department of Nanoscience, United States.

Olufemi Adesola Adedayo

University of Massachusetts, Amherst, School of Natural Sciences, Department of Mathematics and Statistics, United States.

Chiamaka Pamela Agu

Department of Psychiatry, Yale School of Medicine, United States.

Fatimah Adeola Mustapha

Department of Mathematics, Tai Solarin University of Education, Ijagun, Ogun State, Nigeria.

Favour E Odubo

Department of Chemistry and Biochemistry, Baylor University, United States.

Enibokun Theresa Orobator

College of Medicine and Veterinary Medicine, University of Edinburgh, United Kingdom.

*Author to whom correspondence should be addressed.


Abstract

The field of infectious disease prediction and public health response is changing due to the integration of real-time data with machine learning (ML). This paper examines how diverse real-time data types — including mobility patterns, social media activity, wearable sensor data, environmental signals, and electronic health records — can be successfully combined with machine learning approaches to enhance early diagnosis, forecast illness trajectories, and optimize intervention options. The potential of key machine learning models, such as reinforcement learning, deep learning, and supervised learning, to improve forecasting accuracy and facilitate dynamic decision-making is investigated. There is a critical discussion of issues such as algorithmic opacity, privacy problems, data inconsistencies, and a lack of standards. The COVID-19 pandemic case study demonstrates how these tools have already aided in resource allocation and policy planning. A forward-looking outlook on developments in data collecting, explainable Artificial Intelligence, and the necessity of global cooperation is presented in the manuscript's conclusion. When taken as a whole, these elements emphasize how crucial it is to combine technology and international collaboration to fortify public health systems and better prepare for future epidemics. This paper examines how diverse real-time data types — including mobility patterns, social media activity, wearable sensor data, environmental signals, and electronic health records — can be successfully combined with machine learning approaches to enhance early diagnosis, forecast illness trajectories, and optimize intervention options.

Keywords: Global health security, machine learning, predicting infectious disease, COVID-19, pandemic, real-time data


How to Cite

Lawal, Olabisi Promise, Ejikeme Peter Igwe, Adedapo Olosunde, Ezeamii Patra Chisom, Debra Ukamaka Okeh, Adepeju Kafayat OLOWOOKERE, Olufemi Adesola Adedayo, et al. 2025. “Integrating Real-Time Data and Machine Learning in Predicting Infectious Disease Outbreaks: Enhancing Response Strategies in Sub-Saharan Africa”. Asian Journal of Microbiology and Biotechnology 10 (1):147-63. https://doi.org/10.56557/ajmab/2025/v10i19371.

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