Quality Control and Troubleshooting in Histopathology Laboratories

Anjali Chungkham

School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India.

Is-hak Salum Nassor

School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India.

Nasona Lasu Charles

School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India.

Ajit Pal Singh *

Department of Medical Lab Technology, School of Medical and Allied Sciences, Galgotias University, Greater Noida, 203201, India.

*Author to whom correspondence should be addressed.


Abstract

Quality control (QC) and troubleshooting are critical components of histopathology laboratories, ensuring the accuracy, dependability, and uniformity of diagnostic results. This procedure encompasses all stages of laboratory operations, including sample collection, processing, slide preparation, staining, and reporting. Essential quality control measures encompass internal quality control (IQC), external quality assessments (EQA), and proficiency testing, in addition to regular equipment calibration, reagent validation, and personnel training. Troubleshooting is essential for resolving prevalent issues such as tissue artefacts, mislabelling, and inconsistent staining, facilitating prompt identification and rectification of potential errors. Efficient documentation, transparent contact with clinicians, and ongoing improvement initiatives augment laboratory performance. By implementing lean methods, automation, and digital pathology, histology laboratories can improve workflows, maximise resource utilisation, and increase diagnosis accuracy. A culture of quality control and troubleshooting in histopathology ultimately guarantees improved patient outcomes, regulatory compliance, and adherence to the highest standards of diagnostic excellence.

Keywords: Quality control, troubleshooting, histopathology, accuracy, internal quality control, external quality assessment (EQA), proficiency testing, calibration, staining, automation


How to Cite

Chungkham, Anjali, Is-hak Salum Nassor, Nasona Lasu Charles, and Ajit Pal Singh. 2025. “Quality Control and Troubleshooting in Histopathology Laboratories”. Asian Journal of Current Research 10 (4):378-93. https://doi.org/10.56557/ajocr/2025/v10i410053.

Downloads

Download data is not yet available.