Intravenous Lipid Emulsion for the Treatment of Ivermectin Toxicity in a Cat: A Case Report

Vinita Rajpurohit

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

Siraj Ansari *

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

Pallavi Jatoliya

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

Shruti Dehru

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

Ravi Dabas

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

Waseem Farooq

Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly (243122), Uttar Pradesh, India.

*Author to whom correspondence should be addressed.


Abstract

A two-years-old male cat weighing three kg was presented to the Referral Veterinary Polyclinic of ICAR – Indian Veterinary Research Institute (IVRI), Izatnagar with history of anorexia, no water intake, ataxia, head tilting downward, sudden recumbency and loss of vision. While taking history the owner declared about the use of off-label oral ivermectin preparation @ 2.5 mg/kg total dose (5 times the recommended dose) once only. Cat had high rectal temperature (105° F), normal mucus membrane, tachypnoea (70/min), tachycardia(145/min). At the beginning, the patient received 20% lipid emulsion (Intralipid) at 1.5 mL/kg body weight, Diazepam 0.5 mg/kg b. wt. IV once, dexamethasone 0.5 mg/kg b. wt., and 25 mg/kg b. wt. bid of cefotaxime. The patient also received constant rate infusion therapy at 0.25 ml/kg/h, OD, and isotonic crystalloid solution (0.9% NS) at 30 ml/kg body weight for a total of 10 minutes.

After three days, the cat's clinical condition returned to normal state. This case reports helps to readers in managing an emergency condition of ivermectin toxicity.

Keywords: Ivermectin, mydriasis, lipid emulsion therapy, veterinary toxicology


How to Cite

Rajpurohit, V., Ansari, S., Jatoliya, P., Dehru, S., Dabas, R., & Farooq, W. (2024). Intravenous Lipid Emulsion for the Treatment of Ivermectin Toxicity in a Cat: A Case Report. Asian Journal of Current Research, 9(4), 91–94. https://doi.org/10.56557/ajocr/2024/v9i48902