SUBSTITUTED QUINOLINES AS SYNTHONS OF POLYNUCLEAR HETEROCYCLES: AN OVERVIEW

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Published: 2015-08-06

Page: 25-114


MOHAMED ABASS *

Department of Chemistry, Faculty of Education, Ain Shams University, Heliopolis, Cairo 11757, Egypt

AISHA S. MAYAS

Department of Chemistry, Faculty of Education, Sana’a University, Sana’a, Yemen

*Author to whom correspondence should be addressed.


Abstract

The derivatives of quinoline are of chemical interest. They are easy to synthesize and susceptible to subsequent substitution and/or cyclization and ring transformation. The importance of derivation of quinolines to get other polynuclear heterocycles-containing quinoline is due to the fact that quinoline itself plays no part in fundamental metabolism while its fused systems e.g., furo, pyrrolo, indolo, etc. are best-known metabolites. This review covers recent use of quinoline derivatives as synthons of other polynuclear heterocycles.

Keywords: Quinoline, synthesis, heterocyclization, fused quinolines


How to Cite

ABASS, M., & MAYAS, A. S. (2015). SUBSTITUTED QUINOLINES AS SYNTHONS OF POLYNUCLEAR HETEROCYCLES: AN OVERVIEW. Journal of Applied Chemical Science International, 4(1), 25–114. Retrieved from https://ikprress.org/index.php/JACSI/article/view/3304

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