Journal of International Research in Medical and Pharmaceutical Sciences

This study was conducted to investigate the histology, phytochemistry and antimicrobial activities of Coriander (Coriandrum sativum L.) obtained from Omdurman market, Sudan. Histology was conducted by preparations, fixation, dehydration, clearing, wax embedding, sectioning, staining and mounting. Moisture content performed according to FAO manuals. Oil extraction according to British pharmacopeia. Physicochemical according to BS2073. Test of the oil for antimicrobiolcal activity conducted by preparation of extracts, using two concentrations A (2.5) ml which further diluted with 2.5 ml solvent (Methanol) (1:18) to form concentration B and the microorganisms were obtained from Medicinal and Aromatic Plant Institute, National Centre of Research, Sudan. Histological features of Coriander under microscopical examining showing seed coat, outer and inner mesocarp, oil vitae. Other anatomical structures such as endosperms, cuticle epidermis and endocarp were occurred. Phytochemicl investigation of Coriander showed purity (69.5%), moisture content (5.3%), oil content (o.45 % (v/w)), refractive index (1.4523), specific gravity (0.850), odor and taste (anisthole odor), acid value (5.83) and ester value (16.83). Both concentrations A (high concentration) and B (low concentration) showed a low inhibitory effect against Staphylococcus aureus. Concentration A of diluted coriander oil (1:9) showed moderated inhibitory effect against Pseudomonas aeruginosa, Klepsella sp. and E. coli, but concentration B has low inhibitory effect against Pseudomonas aeruginosa, Klepsella sp. and E. coli.