Journal of International Research in Medical and Pharmaceutical Sciences

A cross sectional study (n = 51) was carried out on written consent in a fertility clinic of Sri Lanka during the period of August 2014 to April 2016 to find out whether there is a relationship of serum albumin concentration with seminal parameters such as seminal volume, count, morphology and motility. The study was aimed to find out the biological causes for male infertility due to the fact that the male infertility has become increased in the modern society irrespective of the economic situation. The selected subjects were evaluated for seminal analysis and serum albumin analysis with WHO method of semen analysis and BCG dye binding method of albumin analysis respectively. The relationship between the independent (serum albumin) and each dependent (seminal parameters) was analyzed with Spearman correlation test statistically. Under the outcome, except others the seminal volume was positively correlated to the serum concentration of albumin (P = 0.005, r_s = 0.572). Anyway, this could be due to the composition of seminal volume which compose most of the protein and amino acids such as enzymes as well as coagulators. Even though some clinicians consider the seminal count and motility as the most important parameters which decide the quality of semen, seminal volume also plays a certain role in the function. Thus, it’s important to maintain the serum level of albumin in the normal reference range to have better quality semen, hence fertility.