NOVEL VESICULAR CARRIERS: AN UPDATED REVIEW
NAVJEET KAUR
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar-143001 India.
LAKHVIR KAUR
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar-143001 India.
GURJEET SINGH
*
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar-143001 India.
R. K. DHAWAN
Department of Pharmacology, Khalsa College of Pharmacy, Amritsar, Punjab, India.
STALINJIT SINGH
Department of Medical Laboratory and Technology, Khalsa College of Pharmacy and Technology, Amritsar, Punjab, India.
SAFVAN ALI CHEMBAN
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar-143001 India.
*Author to whom correspondence should be addressed.
Abstract
Novel vesicular drug delivery systems have brought the pharmaceutical industry to a whole new level, by addressing numerous drawbacks associated with drug delivery. Novel drug delivery provides a suitable means of delivering the drug molecules to the desired site of action at a pre-determined rate that is site-specific and time-controlled. The vesicular system functions by encasing active moieties inside the vesicles. Encapsulation of the drug has several benefits, including extended drug existence, improved solubility, increased therapeutic index, and reduced side effects in the systemic circulation. Because of their widespread and extensive use, several novel vesicular carrier systems like liposomes, ethosomes, transferosomes, phytosomes, niosomes, discosomes, archaeosomes, ufosomes have emerged as the preferred vehicle for the delivery of several medications and the development of their formulations. In this review article, we have attempted to assimilate all the relevant knowledge about the recent studies conducted on nanovesicles, following their exploration in the outbreak of Covid-19.
Keywords: Vesicular drug delivery systems, COVID-19, nanovesicles, liposomes, targeted drug delivery, niosomes