ESOMEPRAZOLE MICROCAPSULES: A REVIEW
VISHAKHA VERMA *
Pharmaceutical Regulatory Affairs, JSS College of Pharmacy, JSS Academy of Higher Education, Mysuru, India.
NATASHA THAKUR
MAX Super Speciality Hospital, Saket, New Delhi, India.
. SIMRAN
Sanskar College of Pharmacy and Research, Ghaziabad, India.
BALAMURALIDHARA V.
Pharmaceutical Regulatory Affairs, JSS College of Pharmacy, JSS Academy of Higher Education, Mysuru, India.
*Author to whom correspondence should be addressed.
Abstract
The majority of today’s drug delivery systems are made of bio-degradable, biocompatible and natural bio-polymers, and they can administer drugs at controlled rate. Currently, many research efforts are being made on oral sustained drug delivery system, which is a solid dosing approach. Researchers produced a number of controlled-release and sustained-release dosage formulations by encasing the drug in natural polymer and forming a gel. Micro-beads are characterized as the monolithic sphere that is disseminated throughout the matrix as a molecular dispersion of particle. Esomeprazole microcapsules can also be formulated. Esomeprazole is a drug that is used for treating stomach and esophageal issues (like acid reflux, ulcers). It shows action by lowering the quantity of acid produced by your stomach. It helps symptoms like heartburn, swallowing difficulties, and a persistent cough. This medicine aids in the healing of acid damage to the stomach and esophagus, the prevention of ulcers, and the prevention of esophageal cancer. Proton pump inhibitors (PPIs), such as esomeprazole, are a type of medication. OTC esomeprazole products are used to treat frequent heartburn if you are self-treating with this drug (occurring 2 or more days a week). These medications do not alleviate heartburn immediately away because they take 1 to 4 days to take full action. This review gives information about the methods of preparation and evaluation of esomeprazole microcapsules, along with its advantages and disadvantages.
Keywords: Microcapsules, esomeprazole, proton pump inhibitor, micro beads, heartburn