EVALUATION OF VISUAL FIELD PARAMETERS OF GLAUCOMATOUS PATIENTS UNDER ORAL SUPPLEMENT BY FORSKOLIN, RUTIN AND VITAMINS B1 AND B2

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Published: 2015-01-17

Page: 11-15


ITALO GIUFFRE *

Department of Ophthalmology, Catholic University of Roma, Roma, Italy [IG]

*Author to whom correspondence should be addressed.


Abstract

Purpose: Forskolin, rutin and vitamins B1 and B2 are the main ingredients of a food supplement commercially available in Italy. This drug contributes to a small reduction of IOP in glaucomatous patients who are poorly responsive to multi-therapy treatment. The aim of this study is to report changes of visual field parameters after oral supplement of forskolin, rutin and vitamins B1 and B2.
Patients and Methods: This is a single center, retrospective study. It was conducted on files of 30 (13 M, 17 F) glaucomatous patients and 10 (4 M, 6 F) controls. All these patients were affected by open-angle glaucoma under monotherapy but this association was supplemented only once a day to 30 patients as long as 12 months. The ophthalmological data (IOP, pachymetry, visual field assessment by FDT 30-2 strategy mean deviation and pattern standard deviation) were checked at time 0, 6 months and 12 months from the beginning of the oral therapy.
The statistical analysis was performed by descriptive statistics, one-way ANOVA and Wilcoxon test. Results were considered significantly different when p<0.05.
Results: The two groups were age and sex-matched (p=0.335). The two groups were also matched as for pachymetry (p=0.187). The visual field parameters (mean deviation and pattern standard deviation by FDT 30-2 strategy) were statistically significantly different only at time 12 months (p=0.04).
Conclusion: This study stresses the neuroprotective effect of the association of forskolin, rutin and vitamins B1and B2 from a campimetric point of view.

Keywords: Forskolin, glaucoma, neuroprotection, rutin, visual field, vitamins B1 and B2


How to Cite

GIUFFRE, I. (2015). EVALUATION OF VISUAL FIELD PARAMETERS OF GLAUCOMATOUS PATIENTS UNDER ORAL SUPPLEMENT BY FORSKOLIN, RUTIN AND VITAMINS B1 AND B2. Journal of International Research in Medical and Pharmaceutical Sciences, 1(1), 11–15. Retrieved from https://ikprress.org/index.php/JIRMEPS/article/view/862

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