Journal of Biology and Nature

Sheep remain highly susceptible to infection and frequently develop acute or subacute fasciolosis caused by Fasciola hepatica following ingestion of infective metacercaria present on contaminated pasture and water sources.  The study aims to evaluate the effectiveness of strategic management practices for controlling Fasciolosis in sheep. Two male Muzaffarnagari sheep were presented at RVP, ICAR-IVRI, Bareilly with clinical signs including anorexia, depression, painful bleating, pyrexia, serous nasal discharge, conjunctival pallor and oedema. Faecal examination revealed Fasciola hepatica eggs. Haematological evaluation revealed anaemia and leukocytosis. Serum biochemical analysis indicated hepatic dysfunction and severe hypoproteinemia. One sheep succumbed to infection, and post-mortem examination demonstrated multiple greyish necrotic lesions with haemorrhages and cavities containing numerous Fasciola spp. within bile ducts. Therapeutic management included Triclabendazole bolus @10 mg/kg administered twice at a 3-day interval along with supportive therapy. Deworming of the remaining flock using Triclabendazole @10 mg/kg was advised. Post-treatment faecal examination was negative for fasciolosis, and no further mortality occurred within the flock.