Late-Onset Vulvar Steatocystoma Multiplex: A Rare and Challenging Localization
Yosra Ben Kraiem *
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Hyba Taounza
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Nadia Ismaili
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Mariame Meziane
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Syrine Hamada
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
Laila Benzekri
Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University of Rabat, Rabat, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Aims: To report an exceptionally rare case of vulvar steatocystoma multiplex with late onset and sporadic presentation, and to highlight the role of histopathology in the differential diagnosis of chronic vulvar nodules.
Presentation of Case: A 43-year-old woman with no personal or family history presented with asymptomatic, slowly progressive bilateral nodules on the labia majora that had evolved over one year. Clinical examination revealed multiple well-circumscribed, mobile subcutaneous nodules covered by normal-appearing skin. Histopathological examination showed dermal cystic structures lined by stratified squamous epithelium lacking a granular layer, with sebaceous glands within the cyst wall, confirming steatocystoma multiplex. Surgical excision was performed with a satisfactory outcome.
Discussion: Vulvar steatocystoma multiplex is exceptionally rare; most reported cases occur in familial forms or in older patients. This case is distinguished by its late onset, sporadic nature, and strictly localised vulvar involvement. The differential diagnosis of chronic asymptomatic vulvar nodules is broad, and histopathological confirmation remains essential.
Conclusion: Steatocystoma multiplex should be included in the differential diagnosis of chronic, asymptomatic vulvar nodules. Histopathological examination is the cornerstone of diagnosis, and reporting rare localisations contributes to better recognition of this uncommon condition.
Keywords: Steatocystoma multiplex, vulvar nodules, vulvar cysts, pilosebaceous unit, histopathology, late-onset presentation, sporadic presentation, benign cystic disorder, differential diagnosis, surgical excision