LOW BASED TRIPLE THERAPY FOR ELDERLY PATIENT WITH PRE-LIVER CIRRHOSIS HEPATITIS TYPE C CONTRIBUTES TO IMPROVE HEPATIC FUNCTIONAL RESERVE

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Published: 2017-02-10

Page: 31-35


TORU ISHIKAWA *

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

MICHITAKA IMAI

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

MASAYOSHI KO

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

HIROKI SATO

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

YUJIRO NOZAWA

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

TOMOE SANO

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

AKITO IWANAGA

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

KEIICHI SEKI

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

TERASU HONMA

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

TOSHIAKI YOSHIDA

Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan

*Author to whom correspondence should be addressed.


Abstract

We present the case of an 80-year-old Japanese female suffering from a genotype 1b HCV infection, with a previous history of post-treatment relapse of PEG-IFN (interferon)/ribavirin (RBV). The patient was retreated with telaprevir-based triple therapy, she achieved rapid virological response (RVR). Despite dose reduction of treatment because of adverse effect (AE), she obtained a sustained virological response (SVR). Furthermore, hepatic functional reserve improved.

This case suggests that in selected genotype 1 HCV-infected patients, a successful treatment can be obtained even with a very low dose of these therapy because of AE or reduced compliance for elderly patient with fibrosis.

Keywords: Chronic hepatitis, telaprevir, elderly patients, hepatic functional reserve


How to Cite

ISHIKAWA, TORU, MICHITAKA IMAI, MASAYOSHI KO, HIROKI SATO, YUJIRO NOZAWA, TOMOE SANO, AKITO IWANAGA, KEIICHI SEKI, TERASU HONMA, and TOSHIAKI YOSHIDA. 2017. “LOW BASED TRIPLE THERAPY FOR ELDERLY PATIENT WITH PRE-LIVER CIRRHOSIS HEPATITIS TYPE C CONTRIBUTES TO IMPROVE HEPATIC FUNCTIONAL RESERVE”. Journal of Case Reports in Medical Science 2 (2):31-35. https://ikprress.org/index.php/JOCRIMS/article/view/561.

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