Journal of Case Reports in Medical Science

Herpes Simplex Virus (HSV) encephalitis and Herpes Zoster skin lesions are both caused by different strains of the herpes virus. Herpes Simplex Virus (HSV) encephalitis is caused by the Herpes Simplex Virus (HSV), typically HSV-1, while Herpes Zoster, commonly known as shingles, is caused by the Varicella-Zoster Virus (VZV), which is also a member of the herpesvirus family. This is a case report of HSVE with HZ in a 65 year’s old male patient admitted to hospital with chief complaints of erythematous fluid filled rash over abdomen since 1 week, two episodes of generalised type seizures involved all four limbs and with altered sensorium since 1 day. His past medical history revealed that he was a known case of pulmonary tuberculosis (PTB) 2 years ago and taken antitubercular therapy (ATT) for 6 months and also he had developed chickenpox in his childhood. The patient was diagnosed with herpes skin lesion and herpes simplex virus encephalitis based on his USG report and clinical, neurological symptoms respectively. His laboratory tests revealed abnormal haematology and LFT parameters, USG abdomen showed grade 1 fatty changes with hepatomegaly, echogenic sediments in urinary bladder and herpes zoster eruption in dermatomal distribution, chest X-ray showed suggestive sequalae of pulmonary Koch’s. the treatment was initiated with Acyclovir, Levetiracetam, Tramadol, etc.