A PROSPECTIVE STUDY ON DRUG UTILISATION AND EVALUATION OF ANTI-RETROVIRAL THERAPY AND ANTI-TUBERCULOSIS TREATMENT IN A TERTIARY CARE HOSPITAL
SHAIK MOHAMMED SUHAIL *
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
DIVYA KANDIPALLI
Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
. LAKSHMI
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
ASHOK C. KUMAR
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
M. VENU MADHAV REDDY
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
M. PRAHARSHA LAKSHMI
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
P. SAMUEL CHANDRA
Department of Pharmacy Practice, Srinivasa Institute of Pharmaceutical Sciences, Proddattur, Andhra Pradesh, India.
*Author to whom correspondence should be addressed.
Abstract
Acquired immune deficiency syndrome is the most serious consequence of infection due to HIV which is a major health problem in public. India is with one sixth of world’s population where one of every eight people is HIV infected. Worldwide, tuberculosis is the common serious infection in HIV infected people. WHO estimated that 13% of 8.7 million individuals who develop incidence tuberculosis are co-infected with HIV. The research followed Prospective Observational Study of Anti-retroviral drugs and Anti-tubercular drugs. The total number of drugs for HIV and TB, were collected from inpatient records, as per the prescription, dose, and route of administration. The study involves the above 18 years old patients and it is planned over 6 months of period in ART CENTER. The demographic data and patient characteristics affected with HIV/AIDS and TB group were enrolled in the study. The analysis of study includes, a total number of 220 prescriptions during the research involving 152 males and 52 females and 16 other patients. The drug utility and evaluation for HIV and TB patients were with ART and ATT and with other poly-pharmacy to improve the immune system that is most important in HIV and TB.
Keywords: HIV, tuberculosis, anti-retroviral therapy, anti-tuberculosis treatment, CD4 cells, drug utilization evaluation (DUE), drug utilization review (DUR), drug-drug interactions (DDI), drug related problems (DRPS), Drug therapy management (DTM)