KIKUCHI DISEASE-LIKE INFLAMMATORY PATTERN IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENT: A CASE REPORT
PATARA VORAVUTINON *
Institute of dermatology, Bangkok, Thailand.
PAILIN PUANGPET
Institute of dermatology, Bangkok, Thailand.
*Author to whom correspondence should be addressed.
Abstract
Kikuchi-Fujimoto disease (KFD) is a benign and rare disorder that can be a manifestation of the Kikuchi disease-like inflammatory pattern (KLIP) and coexists with systemic lupus erythematosus (SLE). The corresponding treatment of these diseases is difficult. A 66-year-old Thai man with underlying SLE presented with generalized yellowish erythematous papules and plaques throughout his body. No evidence of fever, lymphadenopathy, or hepatosplenomegaly was noted. Antinuclear antibodies (ANA) were positive but anti-dsDNA, anti-Smith, anti-snRNP, and anti-Ro antibodies were negative. The histopathology was consistent with KFD, and the patient was diagnosed with a Kikuchi disease-like inflammatory pattern. Hydroxychloroquine elicited a rapid and favorable response in the patient who remained relapse-free while on low-dose hydroxychloroquine. Here, we report the case of a 66-year-old Thai man with erythematous plaques on his chest and neck.
Keywords: Kikuchi disease, kikuchi disease-like inflammatory pattern, systemic lupus erythematosus, kikuchi-fujimoto disease