KIKUCHI DISEASE-LIKE INFLAMMATORY PATTERN IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENT: A CASE REPORT
Journal of Disease and Global Health, Volume 15, Issue 1,
Page 18-22
DOI:
10.56557/jodagh/2022/v15i17740
Abstract
Kikuchi-Fujimoto disease (KFD) is a benign and rare disorder that can be a manifestation of the Kikuchi disease-like inflammatory pattern (KLIP) and coexists with systemic lupus erythematosus (SLE). The corresponding treatment of these diseases is difficult. A 66-year-old Thai man with underlying SLE presented with generalized yellowish erythematous papules and plaques throughout his body. No evidence of fever, lymphadenopathy, or hepatosplenomegaly was noted. Antinuclear antibodies (ANA) were positive but anti-dsDNA, anti-Smith, anti-snRNP, and anti-Ro antibodies were negative. The histopathology was consistent with KFD, and the patient was diagnosed with a Kikuchi disease-like inflammatory pattern. Hydroxychloroquine elicited a rapid and favorable response in the patient who remained relapse-free while on low-dose hydroxychloroquine. Here, we report the case of a 66-year-old Thai man with erythematous plaques on his chest and neck.
- Kikuchi disease
- kikuchi disease-like inflammatory pattern
- systemic lupus erythematosus
- kikuchi-fujimoto disease
How to Cite
References
2. Thai LH, Ingen-Housz-Oro S, Godeau B, et al. Kikuchi disease-like inflammatory pattern in cutaneous inflammatory infiltrates without lymph node involvement: A new clue for the diagnosis of lupus? Medicine (Baltimore). 2015;94:e2065.
3. Lalevée S, Moguelet P, Hurabielle C, Senet P, Pha M, Rivière S, et al. Cutaneous kikuchi disease-like inflammatory pattern without lymph node involvement is associated with systemic disease and severe features in lupus erythematous: A case-control study. Lupus. 2020;30(3):473–7.
4. Kuo TT. Kikuchi ́s disease (histiocytic necrotizing lymphadenitis): A clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology and DNA ploidy. Am J Surg Pathol. 1995;19:798-809.
5. Perry AM, Choi SM. Kikuchi-Fujimoto Disease: A Review. archives of pathology & Laboratory Medicine. 2018;142(11): 1341–6.
6. Kim JH, Kim YB, In SI, Kim YC, Han JH. The cutaneous lesions of Kikuchi's disease: a comprehensive analysis of 16 cases based on the clinicopathologic, immunohistochemical, and immunofluorescence studies with an emphasis on the differential diagnosis. Hum Pathol. 2010;41:1245- 54.
7. Song JY, Lee J, Park DW, et al. Clinical outcome and predictive factors of recurrence among patients with Kikuchi's disease. Int J Infect Dis. 2009; 13:322-6.
8. Baenas DF, Diehl FA, Haye Salinas MJ et al. Kikuchi-Fujimoto disease and systemic lupus erythematosus. Int Med Case Rep J. 2016; 9:163-7.
9. Dumas G, Prendki V, Haroche J et al. Kikuchi-Fujimoto disease: Retrospective study of 91 case.
10. Fain O, Braun T, Stirnemann J et al. [Systemic and auto- immune manifestations in myelodysplastic syndromes]. Rev Med Interne. 2011;32:552-9.
11. Treichel AM, Teske N, Vandergriff T, Dominguez A, Mauskar MM, Nguyen KD. Kikuchi disease with cutaneous involvement complicated by features of hemophagocytic lymphohistiocytosis. Journal of Cutaneous Pathology. 2021;48(3):343–6.
12. Vilá LM, Mayor AM, Silvestrini IE. Therapeutic response and long-term follow-up in a systemic lupus erythematosus patient presenting with Kikuchi's disease. Lupus. 2001;10(2):126–8.
13. Rezai K, Kuchipudi S, Chundi V, Ariga R, Loew J, Sha BE. Kikuchi-Fujimoto Disease: Hydroxychloroquine as a treatment. Clinical Infectious Diseases. 2004;39(12).
-
Abstract View: 206 times
PDF Download: 3 times