Prevalence, Profiling and Molecular Identification of Hepatitis B Virus Infection among the Tertiary Students within Birnin Kebbi Metropolis, Nigeria
Maganda J.B *
Department of Microbiology, Kebbi State University of Science and Technology, Aliero, Nigeria.
Manga S.B
Department of Microbiology, Usman Danfodio University, Sokoto State, Nigeria.
Ukatu V.E
Department of Animal and Environmental Biology, Kebbi State University of Science and Technology, Aliero, Nigeria.
Jabaka D.R
Department of Microbiology, Kebbi State University of Science and Technology, Aliero, Nigeria.
Blessing Tunde
Niger State Primary Health Care Development Agency, Mashegu LGA, Nigeria.
Bargu E.J
Department of Physics, Kebbi State University of Science and Technology Aliero, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
A cross sectional study aim the prevalence, profiling and molecular identification of hepatitis B virus infection from the tertiary institutions students in Birnin kebbi metropolis. 329 blood samples were analyzed across the two (2) institutions for HBV using rapid diagnostic kits positive samples were taken for profiling using 5panel cassetes for serological markers and polymerase chain reaction to confirm. The social demographical factors of HBV infection were determine using a structured questionnaire. The prevalence rate of HBV markers at WUFPBK were HBsAg 25(41.25%), HBsAb 3(4.95%), HBeAg 5(8.25%), HBeAb 6(9.9%) HBcAb 15(24.75%) and FUBK: HBsAg 18(29.52%), HBsAb 0(0%), HBeAg 2(3.28%), HBeAb 1(1.64%) and HBcAb 6(9.8%). Seven (7) positives sample indicating HBeAg and HBeAb were used to detected HBV DNA, this indicates the virus replicating in chronic HBV carriers and spread through risks factors associated with HBV.
Keywords: Prevalence, HBV profiling, molecular detection, tertiary institutions, Birnin Kebbi metropolis