Evaluation of Turmeric-Based Unani Formulation for Respiratory Tract Infection: Physicochemical Analysis, HPTLC Fingerprint Screening and Microbiological Studies
Tirumala Santhoshkumar Saripalli *
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Mary Shamya S
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
John Christopher
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Mageswari S
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Wasim Akram
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Mohd Jameel
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Athar Parvez Ansari
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
Sidama Gopal
NRIUMSD, Hyderabad, 500038, India.
Ram Pratap Meena
Central Council for Research in Unani Medicine, Ministry of AYUSH, Government of India, New Delhi, 110058, India.
N. Zaheer Ahmed
Central Council for Research in Unani Medicine, Ministry of AYUSH, Government of India, New Delhi, 110058, India.
Achitya Kumar Mandal
Regional Research Institute of Unani Medicine (NABH and NABL Accredited), Chennai, 600 013, India.
*Author to whom correspondence should be addressed.
Abstract
Respiratory tract infection is a significant non-communicable disease (NCD) that outcomes to significant impairment and fatality on a global scale. The highest number of fatalities occurs in poor and middle-income nations, including Oceania, South and Southeast Asia, the Middle East, and Africa. The World Health Organization (WHO) recognizes and values the significance of medicinal plants in public healthcare in developing countries. The Unani classical literature has several formulas for treating respiratory diseases. Sufoof Dama Haldi Wala is a specific formulation in the unani system using turmeric-based material. However, the quality criteria of this formulation have not been assessed yet. Hence, this work aimed to establish a standardized turmeric-based unani formulation by evaluating its physicochemical properties and doing HPTLC fingerprint screening. The quality requirements have been established by thorough physico-chemical examination. The microbial load test, aflatoxin, and In-vitro antioxidant activity were all within acceptable limits, and no microbes were detected in the produced turmeric based Unani formulation. The elemental analysis has also shown intriguing findings. Standardization of herbal drugs is crucial for ensuring quality control. It enhancing the safety and efficacy of drugs is crucial for delivering optimal treatment to the society. Obtained data for turmeric-based Unani formulation will serve as valuable benchmarks for ensuring the standards and quality control of formulation.
Keywords: Sufoof Dama Haldi Wala, Dama (Asthma), turmeric-based Unani formulation, respiratory tract infection