Pavonia odorata DERIVED PHYTOCHEMICALS AGAINST DERMATOPHYTOSIS
JOGESH KUMAR NAYAK
Centurion University of Technology and Management, Odisha, India.
SURAJ KUMAR SAHU
Centurion University of Technology and Management, Odisha, India.
ELORA BARIK
Centurion University of Technology and Management, Odisha, India.
DIPANKAR BHATTACHARYAY
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Bioactive substance or Phytochemicals from Pavonia odorata plant extract can cure dermatophytosis. It is caused by Trichophyton rubrum. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that hexahydrofarnesyl acetone can effectively deactivate the laccase enzyme thereby interrupting the life cycle of Trichophyton rubrum.
Keywords: Bioactive, phytochemical, Pavonia odorata, Trichophyton rubrum, dermatophytosis