ALZHEIMER TREATMENT USING MEDICINAL PLANTS
SILPI SAIKIA
University Institute of Biotechnology Chandigarh University, Gharuan, India.
LEENA PRAJAPATI
University Institute of Biotechnology Chandigarh University, Gharuan, India.
*Author to whom correspondence should be addressed.
Abstract
Alzheimer is a progressive neurological brain disorder.AD is characterized clinically by cognitive impairment and pathologically by the deposition of β amyloid plaques and neurofibrillary tangles and the degenerative of the cholinergic basal forebrain. The characteristics of AD are changes in personality and behaviour along with anxiety, paranoia, confusion and hallucination. The first neurotransmitter defect discovered in AD involved acetylcholine as cholinergic function is required for short term memory. Oxidative stress can be highlighted as the main reason for progressive neurodegeneration characteristic of AD. The neurotoxicity of β amyloid appears to involve oxidative stress. Many treatment has been carried out for the cure of this disorder. But none of them hassucceeded so far. Traditional medicine is practiced worldwide as memory since ancient times. Herbs and medicinal plants are used in the treatment of the many problems which motivated researchers to use them for treatment of Alzheimer.
Keywords: Alzheimer diseases, PAF, bacopa, ginkgo, ginseng, Ashwagandha, β amyloid, cure, medicine, herbal plants.