PLANT-DERIVED ANTIMICROBIALS (PDAms) TO CONTROL URINARY TRACT INFECTIONS

Main Article Content

ANU KUMAR
RITA SINGH MAJUMDAR

Abstract

Urinary Tract Infection has been recognized second most common infection after respiratory infection and is most frequent in women, accounting for nearly 60% of overall UTIs. Caused by single bacterial species E. coli, which is the most frequently infecting organisms. We undertook this study to know the prevalence of MDR E. coli among various urine samples and to find out antibacterial activity of different herbal extracts against these resistance strains. Out of 40 samples 9 isolates of E .coli (22%) were recovered, which were considered for study. Among these 9 E. coli isolates, 2 (28.6%) were found multiple drug resistant (MDR). The isolates showed high levels of resistance to Amoxycilin (AMX25), Oxacilin (OX1), Ceftazidime (CAZ30) and Ceftriaxone (CTR30). Nine plant species were screened for anti MDR activity and out of  9 plants  the maximum zone of inhibition was observed in the aqueous extract of  Terminalia chebula (22 mm) & Callistemon (22 mm)] which were found  more potent than the previous studies. In conclusion, the prevalence of MDR Producers at our study was lower in comparison to the prevalence reported from other studies. The high rate of resistance in bacteria for antibiotics need alternative drug line to control UTI.

Keywords:
Antimicrobial resistance, Escherichia coli, MDR, UTI

Article Details

How to Cite
KUMAR, A., & MAJUMDAR, R. S. (2020). PLANT-DERIVED ANTIMICROBIALS (PDAms) TO CONTROL URINARY TRACT INFECTIONS. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 21(19-20), 29-34. Retrieved from https://ikprress.org/index.php/PCBMB/article/view/5237
Section
Original Research Article

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