INVESTIGATION OF BACTERIAL INHIBITORY EFFECT OF Solanum trilobatum SEED EXTRACT AGAINST DENTAL PATHOGENS
SUJATHA SARAVANAN
Department of Biotechnology, Bharath Institute of Higher Education and Research, Selaiyur, Chennai-73, India.
GOKUL RAGHAVENDRA SRINIVASAN
Department of Biotechnology, Bharath Institute of Higher Education and Research, Selaiyur, Chennai-73, India.
GEETHA NARAYANASAMY BABU *
Department of Biotechnology, Bharath Institute of Higher Education and Research, Selaiyur, Chennai-73, India.
GUNASEKARAN SHYLAJA
Department of Biotechnology, Bharath Institute of Higher Education and Research, Selaiyur, Chennai-73, India.
*Author to whom correspondence should be addressed.
Abstract
In the current examination, seed extracts of Solanum trilobatum was analysed for its capacity to repress the development of dental pathogens (Staphylococcus aureus, Streptococcus mutans, S. salivarius, S. sanguinis and L. acidophilus). The collected seeds of S. trilobatum were appropriately washed and air dried at room temperature. Then squashed and extracted with acetone, petroleum ether and chloroform. The bacterial inhibitory effect of the extracts was analyzed by ager well diffusion technique at 200 µg/mL concentration. Phytochemical investigation was performed for all the extracts. The results revealed that the root etracts of S. trilobatum was best against all tried bacterial pathogens. Greatest inhibitory action was seen against S. salivarius (22 mm) and less inhibition was against S. sanguinis (9 mm). The phytochemical examination uncovered the wide range of phytoconstituents which may be responsible for its antibacterial potency.
Keywords: Dental pathogens, acetone, bacterial inhibition, seed extract.