In vitro EVALUATION OF ANTIOXIDANT, ANTI-ARTHRITIC ACTIVITY OF Ficus racemosa EXTRACT
T. LAKSHMI *
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 77, Tamil Nadu, India.
ANITHA ROY
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 77, Tamil Nadu, India.
P. E. JAI REXLIN
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 77, Tamil Nadu, India.
S. RAGHUNANDHAKUMAR
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 77, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Ficus racemosa The aim of our study was to evaluate the preliminary phytochemical analysis and in vitro antioxidant activity, anti-arthritic effect of ethanolic fruit extract of F. racemosa. Preliminary phytochemical analysis was done by adopting the method of Evans. Antioxidant assay is performed by ABTS and FRAP assay, Anti arthritic activity was determined by protein denaturation method employing modified method of Mizushtma et al. The present study reveals the presence of few secondary metabolites and the extract exhibits potent antioxidant activity and a concentration dependent protein denaturation activity. From the present study it can be concluded that ethanolic fruit extract of F. racemosa possessed marked in vitro antioxidant and anti-arthritic effect the effect was plausibly due to the presence of phenolic contents of F. racemosa.
Keywords: Phytochemical, antioxidant, F. racemosa, anti-arthritic activity.