ANTIFUNGAL ACTIVITY OF TULSI AND TURMERIC ASSISTED COPPER NANO PARTICLE
A. ROSHAN
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technological Science (SIMATS), Saveetha University, Chennai, India.
A. JOTHIPRIYA
Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
LAKSHMINARAYANAN ARIVARASU
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
RAJESH KUMAR
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
GAYATRI DEVI
Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Nanotechnology applied to medicine and dentistry will bring significant advances in the diagnosis, treatment, and prevention of diseases. Fungal infections are common throughout much of the natural world. In humans, fungal infections occur when an invading fungus takes over an area of the body and is too much for the immune system to handle. Development of more effective and less toxic antifungal agents are required for the treatment of Several fungal diseases. Plants and their extraction preparations have been recently used as medicines against infectious diseases. Tulsi Has several therapeutic mechanisms, including adaptogenic, antimicrobial, anti-inflammatory, cardioprotective and immunomodulatory results. There are various biological effects of turmeric, including anti-inflammatory, antimicrobial and antitumor function properties In this research the main aim of this study is to analyse the Antifungal activity of Tulsi (O. sanctum) and Turmeric(Curcuma longa) assisted with copper nanoparticle, Antifungal activities of the synthesized tulsi and turmeric derivatives were reported against (Candida albicans).
Materials and Methods: Used were 0.5 g turmeric was added to 100 ml of distilled water and boiled for 5 min at 50 degree Celsius. And 1.77 g of CuSo4 was added, after adding copper sulphate and centrifuging, some characteristic colour change was observed in the extract.
Results and Discussion: This samples was used against Candida albicans which was prepared invito. The zone of incubation was 15 mm for dosage of extract in the well of size 150.
Conclusion: This concludes that the combination of Tulsi and turmeric with copper extract has shown better results in anti-fungal activity.