PREPARATION OF SELENIUM NANOPARTICLES USING HERBAL FORMULATION AND ITS ANTIOXIDANT ACTIVITY: AN in vitro STUDY
SAROJINI RAMYA PILLAY
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, India.
ARVINA RAJASEKAR
Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, India.
S. RAJESHKUMAR
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77 India.
*Author to whom correspondence should be addressed.
Abstract
Background: Selenium nanoparticles (Se NPs) have excellent biocompatibility, bioefficacy and low toxicity as compared to various organic and inorganic forms of selenium compounds. Se NPs also exhibit promising therapeutic activity against various oxidative stress and inflammation driven disorders.
Aim: The aim of the study was to check the antioxidant activity of clove and cinnamon herbal formulation.
Materials and Methods: Clove (Syzygium aromaticum) and cinnamon (Cinnamomum verum) were powdered and 5 grams of powdered clove and 5 grams of powdered cinnamon were weighed and mixed with 100 ml distilled water. Aqueous extract was prepared. The extract was then tested for antioxidant activity using DPPH assay.
Results: The aqua alcoholic extract of clove and cinnamon extract showed highest absorbance at a concentration of 10 μl (42.5%) when subjected to DPPH assay to check for its antioxidant activity at a wavelength of 355 nm.
Conclusion: It can be concluded that clove and cinnamon mediated selenium nanoparticles have the potential to be used as an effective antioxidant. Hence it can be employed in large scale production and be used in many medicinal applications.
Keywords: Antioxidant, cinnamon, clove, selenium nanoparticles