CHARACTERIZATION AND ANTI-FUNGAL PROPERTY OF Phyllanthus niruri MEDIATED SILVER NANOPARTICLES

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Published: 2020-08-26

Page: 44-49


PUSHPAANJALI GANAPATHY

Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77, Tamil Nadu, India.

LAKSHMINARAYANAN ARIVARASU

Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai-77, Tamil Nadu, India.

S. RAJESHKUMAR

Department of General Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai-77, Tamil Nadu, India.

*Author to whom correspondence should be addressed.


Abstract

Aim: The Aim of my study is to evaluate the characterization and anti-fungal property of Phyllanthus niruri mediated silver nanoparticles.

Introduction: An environmentally friendly approach is employed to synthesize silver nanoparticles. The biomolecules found in plants induce the reduction of Ag+ ions from silver nitrate to silver nanoparticles (AgNPs). Phyllanthus niruri is an across the board tropical plant regularly found in beach front zones, known by the normal names storm of the breeze, stone-breaker or seed-under-leaf. It is a relative of the purges, having a place with the class Phyllanthus of the family phyllanthaceae. Nanoparticles are a wide class of materials that incorporate particulate substances, which have one measurement under 100 nm in any event. A 20-nm gold (Au), platinum (Pt), silver (Ag), and palladium (Pd) NPs have trademark wine red shading, yellowish dim, dark and dull dark hues, individually.

Materials and Methods: Silver nanoparticle is synthesized by using Phyllanthus niruri, followed by characterization of nanoparticle using UV-VIS spectrophotometer and TEM analysis, a biological activity for antifungal property using agar well diffusion method.

Results: Phyllanthus niruri is a indigenous herb which has been used in India for treatment of various ailments. TEM results showed the size of the nanoparticle to be within 100 nm. The present study showed that the herb of Phyllanthus niruri has an inhibitory effect on growth of Candida albicans.

Conclusion: We concluded that antifungal property of Phyllanthus niruri mediated AgNp is very good and can be used for further investigation.

Keywords: Antifungal property, Candida albicans, Phyllanthus niruri, silver nanoparticle particle


How to Cite

GANAPATHY, P., ARIVARASU, L., & RAJESHKUMAR, S. (2020). CHARACTERIZATION AND ANTI-FUNGAL PROPERTY OF Phyllanthus niruri MEDIATED SILVER NANOPARTICLES. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 21(31-32), 44–49. Retrieved from https://ikprress.org/index.php/PCBMB/article/view/5352

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