GREEN SYNTHESIS OF GOLD NANOPARTICLES USING DIFFERENT MEDICINAL PLANTS AND ITS UV-VIS SPECTROSCOPIC ANALYSIS AND ANTIBACTERIAL ACTIVITY
M. NAGALINGAM
Department of Biochemistry, Indo-American College, Cheyyar, Thiruvannamalai, 604407, Tamil Nadu, India.
S. RAJESHKUMAR
Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, Tamil Nadu, India.
T. LAKSHMI
Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Gold nanoparticles are the most prominent metal nanoparticles and having wide range of applications in drug delivery and many therapeutic potentials.
Materials and Methods: In this present investigation we have used some Indian herbal plants for the green synthesis of gold nanoparticles and its antibacterial efficacy was measured.
Results: The medicinal plants such as Alternanthera bettzickiana, Gymnema sylvestre and Andrographis paniculata used for the synthesis and characterized using UV-vis spectroscopy. The antibacterial activity of gold nanoparticles such as Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus, Enterobacter aerogenes, Salmonella typhi and Pseudomonas aeruginosa.
Conclusion: The plant mediated gold nanoparticles may used in the controlling of pathogens in various medical field.
Keywords: Gold nanoparticles, medicinal plants, UV-Vis, antibacterial activity