PLANT TISSUE CULTURE METHODS IN SECONDARY METABOLITE PRODUCTION – A MINI REVIEW

Main Article Content

SAKSHI SHARMA
SHIVIKA SHARMA
SARVJEET KUKREJA
VIKASH S. JADON
VIKAS SHARMA

Abstract

Plants have always been used as a bio-cultural resource since traditional times, and the plants have always been regarded as the primary producer of natural products from various plant parts like barks, stem, leaves and roots. Plants can produce both primary and secondary metabolites and the use of plant tissue culture methods for the production of secondary metabolites is very much common. These secondary metabolites like alkaloids, phenolics and essential oils play very important role in plant metabolism, i.e. pathogen, insect defense, pigmentation, compounds against herbivores, regulation in germination, growth and development and can also be used by humans for the production of effective drugs and medicine. Different plant - based production methods like callus or suspension culture is being widely used for the production of secondary metabolites from plants. In the recent past, various new methods have been cited which tend to have a more important and renounced effect on the production of secondary metabolites. A knowledge about the recent methods like precursor feeding, elicitation treatment and many more has been reviewed here. Besides plant tissue culture, other technologies like Crispr Cas, nano technology and genome editing are also being used for secondary metabolites production. These plant tissue culture techniques are the best suitable environment friendly techniques that helps in the production of secondary metabolites when chemical synthesis is not feasible or when the natural supply is limited. Thus, an overall comparison is being done regarding the production of secondary metabolites their use and importance to mankind in this mini review.

Keywords:
Secondary metabolites, callus culture, hairy root culture, metabolic engineering, precursor feeding, plant tissue culture, transgenics.

Article Details

How to Cite
SHARMA, S., SHARMA, S., KUKREJA, S., JADON, V. S., & SHARMA, V. (2020). PLANT TISSUE CULTURE METHODS IN SECONDARY METABOLITE PRODUCTION – A MINI REVIEW. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 21(43-44), 144-153. Retrieved from https://ikprress.org/index.php/PCBMB/article/view/5487
Section
Mini Review Article

References

Saurabh Pagare, Manila Bhatia, Niraj Tripathi, Sonal Pagare, Bansal YK, Secondary metabolites of plants and their role: Overview. Current Trends in Biotechnology and Pharmacy. 2015;9(3): 293-304.

Verpoorte R, Alfermann AW. Metabolic engineering of plant secondary metabolism. Dordrecht, The Netherlands: Kluwer Academic Publishers; 2000.

Croteau R, Kutchan TM, Lewis NG. Natural products (secondary metabolites). Biochemistry and Molecular Biology of Plants. 2000;24:1250-1319.

Thirumurugan D, Cholarajan A, Raja SS, Vijayakumar R. An introductory chapter: Secondary metabolites. Second Metab—Sources Appl. 2018;1-21.

Yang L, Wen KS, Ruan X, Zhao YX, Wei F, Wang Q. Response of plant secondary metabolites to environmental factors. Molecules. 2018l23(4):l762.

Alamgir ANM. Biotechnology, In Vitro production of natural bioactive compounds, herbal preparation, and disease management (treatment and prevention). In therapeutic use of medicinal plants and their extracts. Springer, Cham. 2018;2:585-664.

Wilson SA, Roberts SC. Recent advances towards development and commercializa-tion of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal. 2012;10(3):249-268.

Gonçalves S, Romano A. Production of plant secondary metabolites by using biotechnological tools. Secondary Metabolites, Sources and Applications, Intech Open. 2018;81-99.

Sarfaraj M, Rahman MA, Ahmad I, Saeed M. Current approaches toward production of secondary plant metabolites. J Pharm Bioallied Sci. 2012;4:10-20.

Anonymous: In: The wealth of India: A dictionary of Indian raw materials and industrial products. CSIR, New Delhi, India. 1989:2:163-164.

Balandrin MJ, Klocke JA. Medicinal, aromatic and industrial materials from plants. In Bajaj YPS. (ed). Biotechnology in agriculture and forestry. medicinal and aromatic plant. Springer-Verlag, Berlin Heidelberg. 1988;4:1-36.

Endress R. Plant Cell Biotechnology. Springer-Verlag: Berlin. Heidelberg. 1994; 121-255.

Heble MR. High value chemicals by tissue culture. Chem. Ind. Digest. 1993;3:113-118.

Jose CS, Sivaraman K, Singh HP. Medicinal and aromatic plants. Floriculture Today. 2001;24-32.

Kirtikar KR, Basil BD. Indian medicinal plants. Allahabad: Lalit Mohan Basu and Co. 1935;1:764-766.

Ahmad S, Garg M, Tamboli ET, Abdin MZ, Ansari SH. In vitro production of alkaloids: Factors, approaches, challenges and prospects. Pharmacognosy Reviews. 2013;7(13):27.

Abranches R, Marcel S, Arcalis E, Altmann F, Fevereiro P, Stoger E. Plants as bioreactors: a comparative study suggests that Medicago truncatula is a promising production system. Journal of Biotechnology. 2005;120(1):121-134.

Linden JC. Secondary products from plant tissue culture. Biotechnology. 2006;6:1-9.

Rodríguez-Sahagún A, Del Toro-Sánchez CL, Gutierrez-Lomelí M, Castellanos-Hernández OA. Plant cell and tissue culture as a source of secondary metabolites 2012; 3-20(18).

Rao SR, Ravishankar GA. Plant cell cultures: Chemical factories of secondary metabolites. Biotechnol Adv. 2002;20:101-53.

Canter PH, Thomas H, Ernst E. Bringing medicinal plants into cultivation: Opportunities and challenges for biotechnology. Trends Biotechnol 2005;23: 180-5.

Buitelaar RM, Tramper J. Strategies to improve the production of secondary metabolites with plant cell cultures: A literature review. Journal of Biotechno-logy. 1992;23(2):111-141.

Abdin MZ. Enhancing bioactive molecules in medicinal plants. In: Zhu Y, Tan B, Bay B, Liu C, editors. Natural products-Essential resources for human. Singapore: World Scientific Publishing Co. Pvt. Ltd; 2007;45-57.

Dörnenburg H, Knorr D. Strategies for the improvement of secondary metabolite production in plant cell cultures. Enzyme and Microbial Technology. 1995;17(8): 674-684.

Smetanska I. Production of secondary metabolites using plant cell cultures. Adv Biochem Eng Biotechnol. 2008;111:187-228.

Bertoli A, Ruffoni B, Pistelli L, Pistelli L. Analytical methods for the extraction and identification of secondary metabolite production in ‘In vitro’ plant cell cultures. In Bio-Farms for nutraceuticals. Springer, Boston, MA. 2010;250-266.

Jeong GA, Park DH. Enhanced secondary metabolite biosynthesis by elicitation in transformed plant root system: Effect of abiotic elicitors. Appl Biochem Biotechnol. 2006;129:436-46.

Yamanaka M, Ishibhasi K, Shimomura K, Ishimaru K. Polyacetylene glucosides in hairy root cultures of Lobelia cardinalis. Phytochemistry. 1996;41:183-5.

Lake JA, Field KJ, Davey MP, Beerling DJ, Lomax BH. Metabolomic and physiological responses reveal multiphasic acclimation of Arabidopsis thaliana to chronic UV radiation. Plant cell Environ. 2009;32(10): 1377-1389.

Gundlach H, Müller MJ, Kutchan TM, Zenk MH. Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures. Proceedings of the National Academy of Sciences. 1992;89(6):2389-2393.

Gaspar T, Kevers C, Penel C, Greppin H, Reid DM. Thorpe TA. Plant hormones and plant growth regulators in plant tissue culture: A review. In-vitro Cellular and Developmental Biology Plant. 1996;32: 272-289.

Havkln-Frenkel D, Dorn R, Leustek D. Plant tissue culture for production of secondary metabolites. Food Technol. 1997;51(11):56-61.

Hoopen HJG. ten, Vinke JL, Moreno PRH, Verpoorte R, Heijnen JJ. Influence of temperature on growth and ajmalicine production by Catharantus roseus suspension cultures. Enzyme and Microbial Technology. 2002;30:56-65.

Komaraiah P, Naga R. Amrutha, Kavi Kishor PB, Ramakrishna SV. Elicitor enhanced production of plumbagin in suspension cultures of Plumbago rosea L. Enzyme and Microbial Technology. 2002; 31:634—639.

Umamaheswai A, Lalitha V. In vitro effect of various growth hormones in Capsicum annum L. on the callus induction and production of Capsiacin. J Plant Sci. 2007; 2:545-551

Jian Zhao, Wei-Hua Zhu, Qiu Hu, Xing-Wang He. Improved alkaloid production in Catharanthus roseus suspension cell cultures by various chemicals. Biotechnology Letters. 2000;22:1221-1226.

Karwasara VS, Dixit VK. Genetic transformation and elicitation as yield enhancement ‘strategy for glycyrrhizin production by cell cultures of Abrus precatorius L. New Biotechnology. 2009; 25:882.

Heble MR. High value chemicals by tissue culture. Chem. Ind. Digest 1993;3:113-118.

Roberts SC, Shuler ML. Large-scale plant cell culture. Current Opinion in Biotechnology. 1997;8:154-159.

Md. Maruf Hassan, Md. Asraful Alam, F.M. Saflul Azam, Nasima Sharmin, Sharmin Sultana Shampa, Sitara Mahajebin, Rownak Jahan, Mohammed Rahmatullah. Hormonal effect on callus induction of Abrus precatorius L., a widely used medicinal plant. Abstracts/Journal of Biotechnology. 2008;36:47-69.

Taticek RA, Moo-Young M, Legge RL. The scale-up of plant cell culture: Engineering considerations. Plant Cell, Tissue and Organ Culture. 1991;24:139-158.

Jian Zhao, Wei-Hua Zhu and Qiu Hu. Effects oflight and plant growth regulators on the biosynthesis of vindoline and other indole alkaloids in Catharanthus roseus callus cultures. Plant Growth Regulation. 2001;33:43-49.

Aguilar O, Albiter V, Serrano-Carreón L, Rito-Palomares M. Direct comparison between ion-exchange chromatography and aqueous two-phase processes for the partial purification of penicillin acylase produced by E. coli. Journal of Chromatography B. 2006;835(1-2):77-83.

Alfermann AW, Petersen M. Natural product formation by plant cell biotechnology. Plant Cell, Tissue and Organ Culture. 1995;43(2):199-205.

Chinnusamy V, Schumaker K, Zhu JK. Molecular genetics perspectives on cross-talk and specifcity in abiotic stress signaling in plants. J Exp Bot. 2004;55: 225–36.

Shinde Amit N, Malpathak Nutan, Fulzele Devanand P. Optimized production of isoflavones in cell cultures of Psoralea corylifolia L. using elicitation and precursor feeding. Biotechnology and Bioprocess Engineering. 2009;14:612-618.

Ghanati F, Bakhtiarian S. Effect of methyl jasmonate and silver nanoparticles on production of secondary metabolites by Calendula officinalis L (Asteraceae). Tropical Journal of Pharmaceutical Research. 2014;13(11): 1783-1789.