HEMATOLOGICAL STUDY OF AQUEOUS EXTRACT OF Sorghum propinquum LEAVES

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PRAVEEN KUMAR VEMURI
MOHAMMAD ANJUM SHAIK
P. V. HEMANTH SAI
BHAVANA POTLURI
SRI SARVANI VEMURI
GNANASREE BOPPANA
KUSUMA NIDAMANURI
SURYANARAYANA VEERAVILLI

Abstract

Introduction: Sorghum propinquum has been used for a variety of ethnomedicinal purposes, including blood stimulation and purification, as well as body defense.

Aim: The study aims to determine the hematological activity of Sorghum propinquum leaf base extracts.

Methods: The immunological effect of the leaf base extract was evaluated using tests on hematological indices.

Results: The packed cell volume, haemoglobin, red blood cell count, total leucocyte count, monocyte, basophil, eosinophil, bleeding time, and clotting time did not change significantly. The 100 mg/kg dose resulted in a large rise in neutrophils and a considerable decrease in lymphocytes. Platelet count was significantly increased at the dose of 300 mg/kg. Conclusion: The findings did not support the ethnomedicinal usage of the plant leaf base for blood production stimulation. It however showed improvement of non-specific immune responses involving inflammation.

Keywords:
Sorghum propinquum, hematology, phagocytosis, inflammation, ethnomedicinal, immunomodulatory

Article Details

How to Cite
VEMURI, P. K., SHAIK, M. A., SAI, P. V. H., POTLURI, B., VEMURI, S. S., BOPPANA, G., NIDAMANURI, K., & VEERAVILLI, S. (2021). HEMATOLOGICAL STUDY OF AQUEOUS EXTRACT OF Sorghum propinquum LEAVES. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 22(71-72), 151-155. Retrieved from https://ikprress.org/index.php/PCBMB/article/view/7256
Section
Original Research Article

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