VITAMINS C AND E PARTIALLY REVERSE HISTOLOGICAL ALTERATION INDUCED BY ADMINISTRATION OF TETRACYCLINE IN DENTIN OF NEONATE RATS
CAREN SERRA BAVARESCO *
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil and Department of Oral Health, Grupo Hospitalar Conceição, Porto Alegre, RS, Brazil
ANDRE ROTTA SEBBEN
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.
MARCELO GARCIA DASSOW
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil
MYRIAN CAMARA BREW
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil
PEDRO ANTONIO GONZÁLEZ HERNÁNDEZ
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil
ADAIR LUIZ STEFANELLO BUSATO
School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.
*Author to whom correspondence should be addressed.
Abstract
This study sought to verify the role of antioxidants over the intensity of fluorescence in the dental tissue of rats induced by tetracycline. Wistar rats were divided into 4 experimental groups and tooth slides were microscopically observed by fluorescence. Results demonstrated intense fluorescence in the dentine matrix of the slides of the rats which had received tetracycline and slight fluorescence in those which had received tetracycline and vitamin, suggesting partial reverse of oxidative stress. No alterations of fluorescence were observed in the enamel matrix.
Keywords: Tetracycline, tooth discoloration, vitamins C and E, oxidative stress.