Journal of Basic and Applied Research International

The objective of this work was to formulate a stable soluble concentrate formulation of Schiff base (Sch). The Schiff base was synthesised and its structure was confirmed using FTIR and elemental analysis techniques. The formulation was tested in vitro against ten isolates of eight important phytopathogenic fungi by the poisoned food method. In addition, different parameters related to formulation, characterisation and physical stability were determined. The results revealed that the prepared formulation exhibited good stability after preparation at different storage conditions and no separation was observed during the stability test. In addition, the percentage inhibition of mycelial growth of synthesised and formulated Schiff base increases with increasing concentration. The EC₅₀ values of synthesised Schiff base on the tested phytopathogenic fungi; Alternaria citri, Alternaria tenuissima, Lasiodiplodia theobromae, Botrytis cinerea, isolate 1^st Fusarium oxysporum, isolate 2^nd Fusarium oxysporum, Macrophomina phaseolina, Pestalotia longisetula, isolate 1^st Rhizoctonia  solani and isolate 2^nd Rhizoctonia solani were 2268.78, 1556.03, 1320.76, 316.84, 3332.03, 2453, 1127.41, 2511.52, 1022.45 and 870.35 ppm. Whereas, the EC₅₀ values of the soluble concentrate formulation were 91.95, 89.88, 41.20, 38.02, 176.62, 119.41, 34.11, 93.42, 51.14 and 25.54 ppm, respectively. The soluble concentrate formulation has a potential antifungal among control of some phytopathogenic fungi and did not induce side effect on the germination seedlings.