ASSESSMENT OF OXIDATIVE STRESS STATUS OF HYPERTENSIVE SUBJECTS IN KANO, NIGERIA
ZAHIDA M. JIBIR
Department of Biochemistry, Bayero University, PMB 3011, Kano, Nigeria
YUSUF Y. MUHAMMAD *
Department of Biochemistry, Bayero University, PMB 3011, Kano, Nigeria
*Author to whom correspondence should be addressed.
Abstract
The global burden of hypertension is rapidly increasing. Hypertension has been reported to be closely associated to oxidative stress. This work assessed the level of the oxidative marker malondialdehyde and that of the antioxidant, ascorbic acid in hypertensive and healthy control subjects. Results indicate significantly higher malondialdehyde and slightly lower ascorbic acid levels in hypertensives compared to healthy subjects. The results indicate higher oxidative stress and lower antioxidative status in hypertensive compared to the normal research subjects.
Keywords: Hypertension, oxidative stress, malondialdehyde, ascorbic acid, vitamin C.