BIOACTIVE CONSTITUENTS OF Buddleja SPP., AND THEIR THERAPEUTIC POTENTIALS
WAFAA M. HIKAL *
Department of Biology, Faculty of Science, University of Tabuk, P.O. Box 741, Tabuk, 71491, Saudi Arabia and Environmental Parasitology Laboratory, Water Pollution Research Department, Environment and Climate Change Institute, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, 12622, Egypt.
HUSSEIN A. H. SAID-AL AHL *
Medicinal and Aromatic Plants Research Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, 12622, Egypt.
KIRILL G. TKACHENKO
V. L. Komarov Botanical Institute of the Russian Academy of Sciences, 2 Prof. Popova St., Saint Petersburg, 197376, Russia.
*Author to whom correspondence should be addressed.
Abstract
Plants are rich source of natural bioactive phytochemicals. Medicinal plants have ingredients that can treat a disease or can be used to manufacture useful drugs. Herbal medicines are an important part of culture and traditions all over the world. Present review discusses the reported work on the genus Buddleja, due its chemical components and medicinal uses including structures, origins and the potent biologically active natural products isolated from Genus Buddleja, which is known for having many important pharmacologically active substances. The Genus Buddleja have more than 150 species, many of them are distributed in Mediterranean and Asian regions. Traditionally, species of the genus are reported to be used for healing, treatment of liver diseases, bronchial complaints, preventing several other diseases by exhibiting diuretic properties, sedative functions, analgesic potential, antirheumatic actions, antimicrobial activities, anti-hyperglycemic functions and antioxidant properties. A very small number of common species of the Genus Buddleja have been investigated for their biological potential. So, for purposes of the review are shedding light on the plants of the genus Buddleja being promising plants and conducting further examination, study and investigation of their chemical components and biological efficiency.
Keywords: Genus Buddleja, chemical constituents, traditional medicine, biological activities, therapeutic potentials, antioxidant