ANTI-INFLAMMATORY ACTIVITY OF COPPER NANOPARTICLES SYNTHESIZED USING DRIED GINGER
A. SHIVAPRIYA RAJE BHONSLE
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
M. JEEVITHA *
Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
S. PREETHA
Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
S. RAJESHKUMAR
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
*Author to whom correspondence should be addressed.
Abstract
Inflammation is a biochemical reaction of the immune system that can be caused by a broad variety of stimuli, including bacteria, damaged cells and toxic compounds. Ginger (Zingiber officinale) belongs to the Zingiberaceae family. The health-promoting perspective of ginger is attributed to its rich phytochemistry. It is also reported that ginger has anti-inflammatory and antioxidative properties to regulate the aging cycle. Furthermore, it has antimicrobial properties that can aid in the treatment of infectious diseases. Generating free radicals or reactive oxygen species (ROS) during metabolism beyond the antioxidant potential of the biological system results in oxidative stress. The aim of the present study is to evaluate the anti-inflammatory activity of copper nanoparticles using dried ginger. The Zingiber officinale was collected, peeled, washed and air dried in a shady region after which plant extract was prepared and then the copper nanoparticles were synthesized. The synthesis process of copper nanoparticles was periodically observed using UV-Vis spectrophotometer. The anti-inflammatory activity was calculated by the inhibition of albumin denaturation assay test and the results showed that the dried ginger mediated copper nanoparticles had potent anti-inflammatory property.
Keywords: Dried ginger, anti-inflammatory activity, UV-Vis spectroscopy, copper nanoparticles, nanotechnology